Study aims to predict which preterm babies need treatment for a heart vessel that often closes on its own

NCT ID NCT03782610

Ongoing Knowledge-focused Sponsor: Nationwide Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 526 preterm infants born before 30 weeks who have a condition called patent ductus arteriosus (PDA), where a fetal blood vessel stays open too long. Researchers collect heart ultrasound, blood, and urine tests over the first month to predict which babies will close the vessel on their own and which are at risk for lung or brain problems. The goal is to avoid unnecessary treatments and focus care on infants who truly need it.

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Conditions

The condition(s) this trial relates to.

bronchopulmonary dysplasia patent ductus arteriosus Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHOPULMONARY DYSPLASIA NEURODEVELOPMENTAL ABNORMALITY PATENT DUCTUS ARTERIOSUS PRETERM INFANT

Contacts and locations

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Locations

Nationwide Children's Hospital Main Campus Neonatal Intensive Care Unit

Columbus, Ohio, 43205, United States
Nationwide Children's Hospital Neonatal Intensive Care Unit at OhioHealth Grant Medical Center

Columbus, Ohio, 43215, United States
Nationwide Children's Neonatal Intensive Care Unit at OhioHealth Riverside Methodist Hospital

Columbus, Ohio, 43214, United States
Nationwide Children's Neonatal Intensive Care Unit at The Ohio State University Wexner Medical Center

Columbus, Ohio, 43210, United States

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