Brain imaging may predict which depression treatment works for you
NCT ID NCT06002100
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find brain activity patterns that can predict how people with major depression will respond to different treatments. Researchers will use a non-invasive brain imaging device (TD-fNIRS) to measure brain function in 540 adults before they start treatment. The goal is to move toward personalized depression care, where the right treatment is chosen based on individual brain signals.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to personalized depression treatment plans based on brain activity, improving outcomes.
- What could go wrong
- This is an observational study, not a treatment trial. It may not identify reliable biomarkers, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Acacia Clinics
Sunnyvale, California, 94087, United States
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Bespoke Treatment
Los Angeles, California, 90012, United States
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Bespoke Treatment
Los Angeles, California, 90025, United States
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BrainHealth Solutions
Costa Mesa, California, 92626, United States
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Kadima Neuropsychiatry Institute
La Jolla, California, 92037, United States
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Kaizen Brain Center, LLC
La Jolla, California, 92037, United States
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Metro Psychiatry Inc.
Columbus, Ohio, 43215, United States
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Seattle Neuropsychiatric Treatment Center
Bellevue, Washington, 98004, United States
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Seattle Neuropsychiatric Treatment Center
Seattle, Washington, 98104, United States
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UCLA TMS
Los Angeles, California, 90024, United States
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Other studies related to the condition(s) this trial covers.
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