New radiation method aims to improve sarcoma surgery outcomes

NCT ID NCT05224934

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial is testing a new type of radiation therapy given before surgery for retroperitoneal sarcoma, a rare cancer in the abdomen. The radiation is delivered in just five high-dose sessions, targeting the tumor and any nearby nodules. The goal is to see if this approach reduces complications during and after surgery, while still effectively treating the cancer. The study will enroll 50 adults whose tumors can be safely treated with this method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ultra-hypofractionated radiotherapy (stereotactic ablative radiotherapy)

What this could lead to

If successful, this could offer a more effective and safer way to treat retroperitoneal sarcoma before surgery, potentially reducing side effects and improving recovery.

What could go wrong

This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. The radiation dose is high and could cause unexpected side effects or complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

radiation injury retroperitoneal sarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Radiotherapy Department of Cancer Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••