Laser plus gel: new hope for port wine stains?

NCT ID NCT01272609

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding timolol gel to pulsed dye laser treatment could improve results for port wine stains on children's faces. Twenty-five children aged 6 months to 18 years were enrolled, but the study was stopped early. The goal was to see if the combination led to better clearing of the stain compared to laser alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

timolol 1% gel (topical beta-blocker)

What this could lead to

If it worked, this could point toward a more effective treatment for port wine stains in children, reducing the number of laser sessions needed.

What could go wrong

The study was terminated early and only enrolled 25 children, so results are limited. It is unclear if adding timolol gel provides real benefit over laser alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

familial multiple nevi flammei melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CH de Quimper

    Quimper, France

  • CHU de Bordeaux

    Bordeaux, France

  • CHU de Dijon

    Dijon, France

  • CHU de Nice - 4 avenue Reine Victoria

    Nice, Alpes-Maritimes, 06001, France

  • CHU de Touloluse

    Toulouse, 31 0000, France

  • CHU de reims

    Reims, France

  • Clinique Mathilde

    Rouen, France

  • Clinique Saint-jean Languedoc

    Toulouse, France

  • Clinique de Turin

    Paris, France

  • Hôpital Sévigné

    Cesson-Sévigné, France