Laser plus gel: new hope for port wine stains?

NCT ID NCT01272609

Terminated Disease control Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding timolol gel to pulsed dye laser treatment could improve results for port wine stains on children's faces. Twenty-five children aged 6 months to 18 years were enrolled, but the study was stopped early. The goal was to see if the combination led to better clearing of the stain compared to laser alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: timolol 1% gel (topical beta-blocker)
What this could lead to: If it worked, this could point toward a more effective treatment for port wine stains in children, reducing the number of laser sessions needed.
What could go wrong: The study was terminated early and only enrolled 25 children, so results are limited. It is unclear if adding timolol gel provides real benefit over laser alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MELANOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

familial multiple nevi flammei melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA

Contacts and locations

Locations

CH de Quimper

Quimper, France
CHU de Bordeaux

Bordeaux, France
CHU de Dijon

Dijon, France
CHU de Nice - 4 avenue Reine Victoria

Nice, Alpes-Maritimes, 06001, France
CHU de Touloluse

Toulouse, 31 0000, France
CHU de reims

Reims, France
Clinique Mathilde

Rouen, France
Clinique Saint-jean Languedoc

Toulouse, France
Clinique de Turin

Paris, France
Hôpital Sévigné

Cesson-Sévigné, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.