Can a pomegranate peel gel boost gum healing?

NCT ID NCT07725393

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a gel made from pomegranate peel extract, placed directly into deep gum pockets after a standard deep cleaning, can improve healing in people with moderate to advanced gum disease (periodontitis). Thirty-two adults will receive the gel on one side of the mouth and a placebo gel on the other, with gum measurements and inflammatory markers tracked over six months. The goal is to see if this natural extract can reduce pocket depth and attachment loss better than cleaning alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a gel made from pomegranate peel extract, applied directly to the gums after deep cleaning
What this could lead to
If it works, this could offer a simple, natural addition to standard gum disease treatment to improve healing and reduce pocket depth.
What could go wrong
This is a very small, early-stage trial. The gel may not provide any benefit over standard cleaning alone, and natural extracts can vary in potency.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Dental Medicine for Girls, Al-Azhar University

    RECRUITING

    Cairo, Cairo Governorate, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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