New drug cocktail shows promise for rare HIV-Linked cancer

NCT ID NCT02659930

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested whether combining two anti-cancer drugs, pomalidomide (taken as a pill) and liposomal doxorubicin (given through an IV), is safe and tolerable for people with advanced or hard-to-treat Kaposi sarcoma. The study enrolled 62 adults, including those with HIV. The main goal was to find the best dose and check for side effects, while also looking at how the drugs affect quality of life and lung function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

AIDS Kaposi's sarcoma KSHV inflammatory cytokine syndrome Multi-centric Castleman's Disease multicentric Castleman disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States