KAPOSI SARCOMA

This study tests the drug nivolumab in people with advanced rare cancers that have a specific marker (PD-L1). The goal is to see if the drug can shrink or control tumors for at least 12 months. About 28 adults who have not responded to standard treatments will take part.

This early-phase study tests a combination of two drugs, pomalidomide (a pill) and nivolumab (an infusion), in adults with cancers caused by viruses like Epstein-Barr, HPV, or hepatitis. The goal is to find a safe dose and see if the treatment can shrink tumors. The study include…

This study tests a lab-made human protein called CYT107 in 55 adults with HIV and Kaposi Sarcoma (KS), a cancer causing skin and organ growths. The goal is to see if weekly injections for up to 4 weeks can boost T cells and shrink tumors. Participants who improve may get another …

This early-stage study tests a new treatment called MQ710, made from a modified virus, for people with advanced solid tumors that have not responded to standard therapies. The treatment is injected directly into tumors, either alone or with the immunotherapy drug pembrolizumab. T…

This study tests if propranolol, a safe oral drug used for heart conditions, can shrink Kaposi sarcoma tumors in adults. About 25 participants with measurable skin lesions will take the drug and be monitored for response and side effects. The goal is to find a low-cost, accessibl…

This study tests two immunotherapy drugs, PDS01ADC and M7824, for people with advanced Kaposi sarcoma (KS) that has not responded well to prior treatment. The drugs work by helping the immune system recognize and attack KS tumors. About 80 adults will receive the drugs for up to …

This study tests a drug called ixazomib in 41 people with Kaposi sarcoma, a type of skin cancer. The drug works by blocking enzymes that help cancer cells grow. The main goal is to see how many people's tumors shrink or disappear.

This study tests a drug called abemaciclib, currently used for breast cancer, to see if it can safely treat Kaposi sarcoma (KS) in people with or without HIV. About 86 adults with KS will take the drug daily in 28-day cycles. Researchers will monitor for side effects and check if…

This study tests a new 3D imaging device called SkinScan3D to see if it can take better pictures of Kaposi sarcoma (KS) skin lesions than standard 2D photos. The goal is to capture the height and volume of lesions, which may help doctors detect treatment response earlier. About 3…

This study follows 150 adults with Kaposi sarcoma (KS) to understand how the disease develops, changes, and may come back over time. Researchers will collect medical history, perform exams, and take samples like blood, saliva, and tumor biopsies. Participants continue their usual…

This study looks at whether peer-to-peer education and support can help more young people (ages 15-39) living with HIV get screened for cancer and stick with their cancer treatment. The study will enroll 4,100 participants in Zambia. The goal is to reduce cancer deaths in this gr…