New drug cocktail targets rare, aggressive cancer

NCT ID NCT04859465

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether combining two chemotherapy drugs—Abraxane and liposomal doxorubicin—can shrink tumors in people with advanced or unresectable angiosarcoma, a rare and aggressive cancer of blood vessels. The study will enroll 69 patients who have already tried standard treatments. Participants receive the drug combination intravenously every three weeks for up to eight cycles, and researchers will measure how many patients respond to treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Abraxane (albumin-bound paclitaxel) combined with liposomal doxorubicin
What this could lead to
If successful, this could offer a new treatment option for people with advanced angiosarcoma who have run out of standard therapies.
What could go wrong
This is a small, early-phase trial with no control group, so results may not be definitive. The combination may cause significant side effects and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xing Zhang

    RECRUITING

    Guangzhou, Guangdong, 510060, China

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