Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a gel help save jawbone for better dental implants?

NCT ID NCT07771257

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This trial tests whether adding a polynucleotide-hyaluronic acid gel to a standard bone graft helps preserve the jawbone shape after a tooth is removed. Twenty adults needing a tooth extraction and later a dental implant will be randomly assigned to receive either the gel with the graft or the graft alone. Researchers will measure bone changes using 3D scans over six months and take small bone samples at implant placement to see how well the bone regenerates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Polynucleotide-hyaluronic acid gel combined with xenograft bone graft and collagen membrane
What this could lead to
If effective, this combination could improve bone preservation after tooth extraction, potentially leading to better dental implant outcomes and fewer additional bone grafting procedures.
What could go wrong
This is a small early-stage trial with only 20 participants, so results may not apply broadly. The gel could also fail to show added benefit over standard treatment, and there are risks typical of oral surgery, such as infection or poor healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-60 years. * Patients free from systemic diseases affecting wound healing or bone regeneration or contraindicating oral surgery. * Non-smokers with good oral hygiene. * Patients requiring tooth extraction in non-infected sockets due to endodontic failure, non-restorable caries, or trauma, and who will receive implant treatment. * Class I extraction sockets with intact alveolar bone walls. * Presence of teeth adjacent to the extraction site. Exclusion Criteria: * Use of drugs affecting wound healing. * Heavy smokers (\>10 cigarettes/day) or history of substance abuse. * Pregnant or breastfeeding women. * Previous grafting or surgical intervention in the study area. * Uncontrolled and/or untreated periodontal disease (active periodontitis). * Mentally or physically handicapped patients.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Alveolar ridge preservation are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    Cairo, Cairo Governorate, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.