Which dental biomaterial works best when left exposed in the mouth?

NCT ID NCT07589751

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Pontificia Universidade Católica do Rio Grande do Sul Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

After a tooth is pulled, the bone can shrink, making it harder to place dental implants later. This study tests two collagen-based biomaterials that are left exposed to the mouth to see how well they preserve bone. Sixty adults needing a single tooth extraction will be randomly assigned to one of two biomaterials or natural healing. Researchers will measure bone changes, bacterial contamination, and patient comfort to help dentists choose the best option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bio-Oss Collagen® and Bio-Gide® or Mucograft® Seal®
What this could lead to: If successful, this could help dentists choose safer biomaterials for preserving bone after tooth extraction, improving future dental implant success.
What could go wrong: This is a small, early-stage study with only 60 participants, so results may not apply to all patients. The biomaterials are left exposed to saliva and bacteria, which could affect healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR RIDGE PRESERVATION TOOTH EXTRACTION SITE HEALING

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Locations

PUCRS

Porto Alegre, Rio Grande do Sul, 90619900, Brazil

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