New drug combo trial offers hope for Hard-to-Treat prostate cancer
NCT ID NCT06785636
First seen Nov 17, 2025 · Last updated May 11, 2026 · Updated 29 times
Summary
This study tests a new drug called pocenbrodib, either by itself or combined with other treatments, in people with a type of advanced prostate cancer that no longer responds to hormone therapy. The goal is to find the safest dose and see if it helps shrink tumors or lower PSA levels. About 252 adults with metastatic castration-resistant prostate cancer will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Cancer and Blood Research Center
RECRUITINGLos Alamitos, California, 90720, United States
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Community Health Network
RECRUITINGIndianapolis, Indiana, 46250, United States
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Duke University medical center
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
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Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
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MemorialCare Orange Coast Medical Center
RECRUITINGFountain Valley, California, 92708, United States
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Mount Sinai Medical Center
RECRUITINGMiami, Florida, 33140, United States
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NEXT Oncology - Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Nebraska Cancer Specialists
RECRUITINGOmaha, Nebraska, 68130, United States
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Ochsner
RECRUITINGJefferson, Louisiana, 70121, United States
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Oncology Consultants, P.A
RECRUITINGHouston, Texas, 77030, United States
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Siteman Cancer Center
RECRUITINGSt Louis, Missouri, 63108, United States
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Taylor Cancer Research Center
RECRUITINGMaumee, Ohio, 43537, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Colorado Health
RECRUITINGAurora, Colorado, 80045, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Conditions
Explore the condition pages connected to this study.