New hope for kids with rare brain cancer: trial combines chemo and radiation
NCT ID NCT06861244
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study tests a combination of chemotherapy and focused radiation in children newly diagnosed with a rare brain tumor called ETMR. About 70 children will receive standard treatments to see if this approach helps keep the tumor from growing for at least 6 months. The goal is to find a better way to control this aggressive cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Chemotherapy (e.g., cytarabine, carboplatin) and radiation therapy
- What this could lead to
- If successful, this could improve survival rates and establish a standard treatment for children with ETMR, a rare and aggressive brain tumor.
- What could go wrong
- This is a Phase 2 trial with only 70 participants, so results may not apply to all patients. The treatments involve strong chemotherapy and radiation, which can have serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21218, United States
-
Riley Hospital for Children at Indiana University Health
RECRUITINGIndianapolis, Indiana, 46202, United States
-
St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
-
University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
-
University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Email: •••••@•••••
-
University of Utah
RECRUITINGSalt Lake City, Utah, 84113, United States
-
Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63130, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Rare brain tumor registry launches to unlock secrets of ETMR
- Immune cells engineered to fight brain cancer in kids
- Tailor-Made T-Cells take on childhood brain cancer
- New hope for toddlers with aggressive brain cancer: experimental spinal-fluid chemo
- New pill combo offers hope for kids with relapsed cancers