Immune cell webs linked to worse outcomes in chest infection

NCT ID NCT07194915

Ongoing Knowledge-focused Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines whether tiny webs released by immune cells, called neutrophil extracellular traps (NETs), are linked to how severe a pleural infection is and the risk of dying within a year. Researchers analyzed fluid from the chest cavity of 326 patients across multiple countries. The goal is to better understand the disease and potentially identify high-risk patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify which patients with pleural infection are at highest risk, guiding more personalized treatment decisions.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not apply to all patient groups or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PLEURAL INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Inflammation pleural empyema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLEURAL INFECTION

Contacts and locations

Locations

CAMS Oxford Institute, Nuffield Department of Medicine

Oxford, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.