Could blood fats be the key to predicting dangerous clots?
NCT ID NCT07774845
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This study explores whether higher levels of fats in the blood might reduce platelet clumping, which could lower clot risk. Researchers will compare how platelets react with and without lipid nanoemulsions in blood samples from healthy adults aged 40 and older. The goal is to develop a new method to assess clot risk and potentially identify a target for future treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lipid nanoemulsions
- What this could lead to
- If this works, it could lead to a new blood test that predicts clot risk and possibly a target for preventing blood clots.
- What could go wrong
- This is a small, early lab study, not a treatment trial. The findings may not translate to real-world clot prevention, and the emulsions are only tested in the lab, not in the body.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Eligible individuals satisfying the standard wellness criteria.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women aged ≥ 40 years. * Willingness to sign the informed consent form. * Absence of known atherosclerotic disease Exclusion Criteria: * Use of antiplatelet agents. * Use of anticoagulants. * Use of lipid-lowering agents. * Use of oral hypoglycemic agents or insulin. * Known atherosclerotic disease. * Refusal to sign the informed consent form
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Heart Institute, University of São Paulo Medical School (InCor/HCFMUSP)
RECRUITINGSão Paulo, São Paulo, 05403-900, Brazil
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