Gene test may cut chemo side effects

NCT ID NCT04541381

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether giving doctors a patient's genetic information can help them personalize chemotherapy doses and reduce serious side effects. About 860 adults with certain cancers (like breast, stomach, or head and neck) will be randomly assigned to have their doctors receive genetic test results or not. The goal is to see if this approach leads to fewer severe toxicities and better dose management.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm digestive system cancer digestive system neoplasm dihydropyrimidine dehydrogenase deficiency head and neck cancer Head and Neck Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Chicago Medical Center

    Chicago, Illinois, 60637, United States