Heart zapping study checks if AFib fix lasts

NCT ID NCT07620262

Recruiting now Disease control Sponsor: Northwell Health Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study looks at whether pulsed field ablation (PFA), a standard treatment for atrial fibrillation, creates lasting changes in the heart's electrical pathways. Researchers will check this during a follow-up procedure to close the left atrial appendage, and may do extra ablation if needed. About 50 adults with AFib and a high stroke risk are being enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pulsed field ablation (PFA) and left atrial appendage occlusion (LAAO) device
What this could lead to: If successful, this could confirm that PFA provides lasting isolation of faulty heart signals, potentially reducing the need for repeat procedures in atrial fibrillation patients.
What could go wrong: This is a small, early-stage study (50 participants) with no control group, so results may not apply broadly. The procedure itself carries risks like bleeding, infection, or heart rhythm issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATRIAL FIBRILLATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF)

Contacts and locations

Locations

South Shore University Hospital
RECRUITING

Bay Shore, New York, 11706, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.