New PET scan could spot radiation injury early

NCT ID NCT04485286

Recruiting now Diagnosis Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special PET probe called [68Ga]CBP8 to see if it can detect tissue damage caused by radiation therapy in people with lung or pancreatic cancer. About 72 participants will get a PET scan before and 3-6 months after radiation. The goal is to find early signs of radiation fibrosis, which could help doctors manage side effects better.

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Conditions

The condition(s) this trial relates to.

Fibrosis lung cancer lung neoplasm malignant pancreatic neoplasm non-small cell lung carcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm Radiation Fibrosis Syndrome radiation pneumonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER PANCREAS CANCER RADIATION FIBROSIS RADIATION-INDUCED LUNG INJURY

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Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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Contact Phone: •••-•••-•••• Email: •••••@•••••

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