New knee system tracked in 700-Patient study

NCT ID NCT03495232

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 700 people receiving a Persona total knee replacement to see how well the artificial joint works over time. Researchers will measure pain, function, and quality of life using patient questionnaires, and track how long the implant lasts (up to 10 years). The goal is to understand the real-world performance and safety of this knee system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Zimmer Biomet Persona total knee system (artificial knee joint)
What this could lead to
If successful, this could confirm that the Persona knee system provides good pain relief and function for at least 10 years after surgery.
What could go wrong
This is an observational study, not a randomized trial comparing treatments. Results may not apply to all patients, and some may still experience complications or need revision surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Copenhagen University Hospital, Hvidovre

    Copenhagen, Denmark

  • Institute Locomoteur de L'Ouest

    Saint-Grégoire, 35760, France

  • Ortopedic Clinic, Motala Specialist Care Capio AB

    Motala, Sweden

  • St Olavs Hospital

    Trondheim, Norway

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