New immune score aims to predict infections in transplant patients

NCT ID NCT07379554

Recruiting now Knowledge-focused Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is developing a personalized immune score to predict severe infections in people with weakened immune systems, such as transplant recipients. Researchers will measure different immune cells and virus-specific responses in 150 adult and pediatric patients before or one month after transplant or chemotherapy. The goal is to identify those at high risk for serious infections within the next three months, allowing for more tailored monitoring and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test that helps doctors predict and prevent serious infections in transplant patients.
What could go wrong: This is an early-stage observational study with only 150 participants, so the results may not apply to all patients. The immune score needs further validation before it can be used in routine care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNOCOMPROMISED PATIENTS INFECTIONS TRANSPLANT PATIENTS

Contacts and locations

Locations

Fondazione IRCCS Policlinico San Matteo
RECRUITING

Pavia, Lombardy, 27100, Italy

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