Heart shield after COVID: new trial tests exercise and meds to stop heart failure

NCT ID NCT04983823

Recruiting now Prevention Sponsor: Baker Heart and Diabetes Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a special heart-care plan, including better medication and exercise, can prevent heart failure in people over 50 who had COVID-19. Researchers will measure changes in exercise capacity and watch for new heart failure symptoms. The trial aims to enroll 820 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cardiac COVID Disease Management Plan (CC-DMP) including optimal medication and exercise
What this could lead to: If it works, this could point toward a simple, low-cost strategy to prevent heart failure in older adults who had COVID-19.
What could go wrong: This is a relatively early feasibility study, not a large Phase 3 trial. The intervention combines medication and exercise, so it's hard to know which part helps. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19 heart failure prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Baker Heart and Diabetes Institute
RECRUITING

Melbourne, Victoria, 3004, Australia

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