Immunotherapy shows promise against mouth precancers

NCT ID NCT02882282

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 27 times

Summary

This study tested the drug pembrolizumab (Keytruda) in 15 people with high-risk precancerous mouth lesions. The goal was to see if the drug could prevent these lesions from turning into oral cancer. Participants were randomly assigned to receive the drug or just be watched. The study looked at how long people stayed cancer-free and overall survival.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.