Immunotherapy drug shows promise in blocking oral cancer in High-Risk patients

NCT ID NCT02882282

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study tested whether the immunotherapy drug pembrolizumab (Keytruda) can help prevent oral cancer in 15 people with high-risk precancerous mouth lesions. Participants were randomly assigned to receive the drug or be observed. The goal was to see if the drug could keep the lesions from turning into cancer. The trial is now complete, and results help guide future prevention strategies.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.