Could a common diabetes drug stop oral cancer before it starts?

NCT ID NCT02581137

First seen Mar 09, 2026 · Last updated May 17, 2026 · Updated 10 times

Summary

This study tests whether metformin, a drug used for diabetes, can prevent oral cancer in people with precancerous mouth lesions (leukoplakia or erythroplakia). About 26 participants took metformin to see if their lesions shrank or disappeared. The goal is to find a simple way to stop these lesions from turning into cancer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ERYTHROPLAKIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • BC Cancer Research Centre

    Vancouver, British Columbia, V5Z 1L3, Canada

  • UC San Diego Medical Center - Hillcrest

    San Diego, California, 92103, United States

  • University of British Columbia Hospital

    Vancouver, British Columbia, V6T 2B5, Canada

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.