ORAL LEUKOPLAKIA
Clinical trials for ORAL LEUKOPLAKIA explained in plain language.
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Could a common diabetes drug stop precancerous mouth lesions?
Disease control Recruiting nowThis study tests whether metformin, a diabetes drug, can shrink or prevent precancerous mouth patches called oral leukoplakia. Researchers will give 34 adults a metformin gel applied to the lesion plus a metformin pill, or placebos. The goal is to see if the combination reduces l…
Matched conditions: ORAL LEUKOPLAKIA
Phase: PHASE2 • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Kitchen spices meet science: can curcumin and CoQ10 gels stop mouth cancer before it starts?
Disease control Recruiting nowThis study tests whether gels made with coenzyme Q10 or curcumin can shrink or stabilize precancerous white patches in the mouth called oral leukoplakia. About 34 adults with mild patches that don't need surgery will apply the gel daily. The goal is to see if these antioxidants c…
Matched conditions: ORAL LEUKOPLAKIA
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Diabetes drugs may zap precancerous mouth lesions in new trial
Disease control Recruiting nowThis study tests whether a combination of two diabetes drugs, pioglitazone and metformin, can shrink or improve precancerous patches in the mouth called oral leukoplakia. About 36 adults with high-risk lesions will take the pills twice daily for 12 weeks. The goal is to see if th…
Matched conditions: ORAL LEUKOPLAKIA
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New imaging tool could make mouth biopsies more accurate
Diagnosis Recruiting nowThis study tests a new imaging device called the Active Biopsy Guidance System to help doctors decide when and where to take tissue samples (biopsies) from mouth lesions. About 90 adults with suspicious mouth spots or a history of oral cancer will participate. The goal is to see …
Matched conditions: ORAL LEUKOPLAKIA
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:08 UTC
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New study aims to unlock secrets of oral cancer through tissue and symptom tracking
Knowledge-focused Recruiting nowThis study is for 1000 people with oral cancer or precancerous mouth lesions. Researchers will collect tissue samples and ask participants about their symptoms before, during, and after treatment. The goal is to find better ways to predict how the disease will behave and which tr…
Matched conditions: ORAL LEUKOPLAKIA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC