Plastic vs. metal: new knee implant trial aims for better replacement
NCT ID NCT06627673
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a new plastic (PEEK) knee implant to a standard metal one in 200 people with severe knee osteoarthritis who need total knee replacement. The goal is to see if the plastic implant works just as well as metal in terms of pain relief, movement, and safety. Participants will be followed for several years to track outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PEEK-OPTIMA femoral component (a plastic knee implant)
What this could lead to
If it works, this could offer a lighter, potentially longer-lasting alternative to metal knee implants for people needing total knee replacement.
What could go wrong
This is an early-stage device trial with only 200 participants, so results may not apply to everyone. The new plastic implant could wear out faster or cause unexpected complications compared to metal.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ascentis
RECRUITINGLeawood, Kansas, 66211, United States
Contact
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South Texas Bone and Joint
RECRUITINGSan Antonio, Texas, 78249, United States