Experimental vaccine aims to shrink colorectal tumors before surgery
NCT ID NCT06692959
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tested a vaccine called PD1-Vaxx given before surgery to people with a specific type of colorectal cancer (MSI-high). The goal was to see if the vaccine could shrink tumors, measured by how many cancer cells remained after treatment. Only 3 people took part, and the study was stopped early, so we don't have clear answers yet.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PD-1 vaccine (PD1-Vaxx)
What this could lead to
If it works, this could point toward a way to shrink tumors before surgery in certain colorectal cancers.
What could go wrong
This was a very early, small trial that was terminated early with only 3 participants, so results are limited and may not apply broadly.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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St John of God Subiaco Hospital
Perth, Western Australia, Australia
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The Queen Elizabeth Hospital
Adelaide, South Australia, Australia