PCOS treatments put to the heart test

NCT ID NCT06889454

Recruiting now Knowledge-focused Sponsor: Attikon Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how different treatments for Polycystic Ovary Syndrome (PCOS) affect the heart and blood vessels. Researchers will compare four approaches: a GLP-1 receptor agonist, birth control pills, metformin, and lifestyle changes alone. They will measure changes in heart function and artery stiffness in 120 women with PCOS over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: GLP-1 receptor agonist, oral contraceptive, metformin, lifestyle modification
What this could lead to: If successful, this could help doctors choose PCOS treatments that also protect heart health.
What could go wrong: This is an early-stage study with only 120 participants, so results may not apply to all women with PCOS. It measures markers, not long-term health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Hyperandrogenism hyperinsulinism metabolic syndrome X polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERANDROGENISM HYPERINSULINISM METABOLIC SYNDROME PCOS

Contacts and locations

Locations

Attikon University General Hospital
RECRUITING

Chaïdári, 124 62, Greece

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