Stents plus drugs vs. drugs alone: which is better for heart failure?

NCT ID NCT07349979

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two approaches for people with heart failure and narrowed heart arteries: a stent procedure plus guideline-directed medications versus medications alone. About 1,150 participants will be followed for at least two years to see which group has fewer major heart problems like heart attacks, hospitalizations, or death. The goal is to find out if adding a stent improves outcomes beyond what medications can achieve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
heart stent procedure (percutaneous coronary intervention) plus standard heart failure medications
What this could lead to
If it works, this could show that combining stents with medications is better than medications alone for preventing heart attacks, hospitalizations, and death in people with heart failure.
What could go wrong
This trial hasn't started yet, so results are years away. The procedure carries risks like bleeding or vessel damage, and the benefit over medications alone may be small or absent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nanjing First Hospital, Nanjing Medical University

    Nanjing, Jiangsu, 210006, China

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