Parkinson's drug holiday: can a week off meds reveal the Disease's true face?

This study looked at whether it's possible and safe for people with early-stage Parkinson's disease to stop their medication for one week while being monitored with brain scans and wearable sensors. Twenty participants were followed to see how their symptoms and brain activity changed off meds. The goal was to find better ways to measure the disease itself, not just the effect of drugs, which could help future trials of treatments that aim to slow or stop Parkinson's.