Skin prick may reveal Parkinson's progression

NCT ID NCT06621602

First seen Nov 19, 2025 · Last updated May 01, 2026 · Updated 25 times

Summary

This study looks at whether a small skin sample can measure a protein called phosphorylated alpha-synuclein, which is linked to Parkinson's disease and REM sleep behavior disorder. Researchers will follow 100 adults aged 50 to 85 for 18 months to see if changes in this protein match changes in symptoms. The goal is to find a simple way to track the disease over time.

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Contacts and locations

Locations

  • Atlanta NeuroScience Institute ANI

    Atlanta, Georgia, 30327, United States

  • Aventura Neurologic Associates, LLC

    Aventura, Florida, 33180, United States

  • Boston Neuro Research Center

    Boston, Massachusetts, 02747, United States

  • CND Life Sciences

    Scottsdale, Arizona, 85258, United States

  • Cedars Sinai

    Los Angeles, California, 90048, United States

  • MedStar Montgomery Medical Center

    Olney, Maryland, 20832, United States

  • Movement Disorders Center of Arizona

    Scottsdale, Arizona, 85258, United States

  • Neurology Multidisciplinary Clinic at Norton Healthcare

    Louisville, Kentucky, 40241, United States

  • Parkinson's Disease and Movement Disorders Center - Boca Raton

    Boca Raton, Florida, 33486, United States

  • Parkinson's Disease and Movement Disorders Center at KUMC

    Kansas City, Kansas, 66160, United States

  • Parkinson's Research Centers of America - Long Island

    Commack, New York, 11725, United States

  • Parkinson's Research Centers of America - Orange County

    Aliso Viejo, California, 92656, United States

  • Parkinson's Research Centers of America - Palo Alto

    Palo Alto, California, 94301, United States

  • The Medical University of South Carolina

    Charleston, South Carolina, 29403, United States

  • UT Health San Antonio

    San Antonio, Texas, 78229, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Rochester

    Rochester, New York, 14618, United States

  • Veracity Neuroscience LLC

    Memphis, Tennessee, 38157, United States

Conditions

Explore the condition pages connected to this study.