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Mind over back pain: brain retraining therapy tested for chronic sufferers

NCT ID NCT07696741

Recruiting now Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 24, 2026 · Updated 4 times

Summary

This pilot study tests whether Pain Reprocessing Therapy (PRT) — a psychological treatment that teaches people to reinterpret pain signals from the brain — is feasible and acceptable for working-age adults (18–65) with chronic low back pain. Participants are randomly assigned to either 8 weekly PRT sessions or a monitoring and education program. The study measures recruitment, retention, satisfaction, and changes in pain intensity and daily functioning, with follow-up at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pain Reprocessing Therapy (psychological intervention)
What this could lead to
If effective, this therapy could offer a drug-free way to manage chronic low back pain by retraining how the brain processes pain signals.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply to everyone. The therapy requires active participation and may not work for all types of back pain.

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Conditions

The condition(s) this trial relates to.

agnosia Back Pain Chronic Pain Low Back Pain Nociplastic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LOW BACK PAIN (CLBP) NOCIPLASTIC PAIN

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toronto Rehabilitation Institute - University Centre

    RECRUITING

    Toronto, Ontario, M5G 2A2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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