Can retraining your brain ease back pain? new study investigates

NCT ID NCT05820204

Ongoing Symptom relief Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This study compares three approaches for chronic back pain: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT), and usual care. Researchers want to see if PRT helps lower pain intensity and improve daily functioning. The trial enrolls 150 racially and ethnically diverse adults with ongoing back pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pain Reprocessing Therapy (PRT) – a type of talk therapy that helps the brain reinterpret pain signals
What this could lead to: If PRT works well, it could offer a new, drug-free way to reduce chronic back pain for people who haven't found relief with other treatments.
What could go wrong: This is an early feasibility study, not a large-scale trial. PRT is new and may not work better than existing therapies like CBT. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Back Pain Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACK PAIN PAIN, CHRONIC

Contacts and locations

Locations

University of Colorado Anschutz Medical Campus

Aurora, Colorado, 80045, United States

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