Can retraining your brain ease back pain? new study investigates

NCT ID NCT05820204

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares three approaches for chronic back pain: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT), and usual care. Researchers want to see if PRT helps lower pain intensity and improve daily functioning. The trial enrolls 150 racially and ethnically diverse adults with ongoing back pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pain Reprocessing Therapy (PRT) – a type of talk therapy that helps the brain reinterpret pain signals

What this could lead to

If PRT works well, it could offer a new, drug-free way to reduce chronic back pain for people who haven't found relief with other treatments.

What could go wrong

This is an early feasibility study, not a large-scale trial. PRT is new and may not work better than existing therapies like CBT. Results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Back Pain Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Anschutz Medical Campus

    Aurora, Colorado, 80045, United States