New pill could ease pain after wisdom tooth surgery
NCT ID NCT07511816
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests a single oral dose of LY4515100 against a placebo in 212 people with moderate-to-severe pain after having their wisdom teeth removed. The goal is to see if the drug safely reduces pain intensity and how quickly it works. Participants stay in a research unit for about 6 weeks after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- LY4515100
- What this could lead to
- If it works, this could provide a new, fast-acting painkiller for short-term pain after dental surgery.
- What could go wrong
- This is an early Phase 2 trial with only 212 people, so results may not apply to everyone. The drug is compared to placebo, and its safety and effectiveness are still unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
JBR Clinical Research
RECRUITINGSalt Lake City, Utah, 84107, United States
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