Patch over pill? new study tests pain relief after root canal

NCT ID NCT07610265

Completed Symptom relief Sponsor: Nims University Rajasthan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether pain-relieving skin patches work as well as oral tablets for pain after root canal treatment. 80 adults with tooth pain received either a ketoprofen or fentanyl patch, or an oral medication. They rated their pain over 48 hours. The goal was to see if patches could be a good alternative to pills.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ketoprofen transdermal patch and fentanyl transdermal patch
What this could lead to: If successful, this could show that skin patches offer a convenient alternative to oral painkillers after root canal treatment.
What could go wrong: This is a small, completed Phase 4 trial with only 80 participants. Results may not apply to everyone, and skin patches can cause local irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST ENDODONTIC PAIN

Contacts and locations

Locations

Department of Conservative Dentistry and Endodontics, Nims Dental College and Hospital, Nims University, Rajasthan

Jaipur, Rajasthan, 303121, India

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