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Teaching the brain about pain may boost exercise benefits for chronic pain sufferers

NCT ID NCT07693998

Symptom relief Sponsor: University of Valencia Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether combining pain neuroscience education (teaching people how the brain processes pain) with therapeutic exercise helps people with fibromyalgia or chronic low back pain. Participants attend exercise sessions three times a week and one education session weekly for eight weeks. The control group does the same exercise but receives basic anatomy lessons instead of pain education. Researchers measure pain, movement quality, disability, and nervous system function to see if the combined approach leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pain neuroscience education combined with therapeutic exercise
What this could lead to
If it works, this approach could offer a non-drug way to reduce pain and improve movement and quality of life for people with chronic pain conditions like fibromyalgia and low back pain.
What could go wrong
This is a relatively small study (84 participants) and the control group also gets exercise, so the added benefit of the pain education may be modest. Results may not apply to all chronic pain patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Fibromyalgia (FM) Inclusion Criteria: * Diagnosis of fibromyalgia according to the 2010/2011 American College of -Rheumatology criteria * Ability to understand and follow study instructions (Mini-Mental State Examination \[MMSE\] score \>23) Exclusion Criteria: * Changes in medication during the month prior to enrollment * Disorders affecting the central or peripheral nervous system Chronic Low Back Pain (CLBP) Inclusion Criteria: * Chronic low back pain lasting at least 3 months * Low back pain occurring on 3 or more days per week * Pain located between the lower rib margin and the gluteal folds * Ability to understand and follow study instructions (Mini-Mental State Examination \[MMSE\] score \>23) Exclusion Criteria: * Changes in medication during the month prior to enrollment * Disorders affecting the central or peripheral nervous system * History of spinal surgery

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome fibromyalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic low-back pain (CLBP) Chronic pain Fibromyalgia (FM)

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Facultat de Fisioteràpia

    Valencia, Valencia, 46010, Spain

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