Shoulder surgery pain showdown: catheter vs. single shot
NCT ID NCT05868330
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two methods of numbing the shoulder after total shoulder replacement: a continuous catheter that delivers pain medicine over time versus a single injection of long-lasting medication. About 56 adults having shoulder replacement will be randomly assigned to one of the two groups. The goal is to see which approach provides better pain control and function on the first day after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 56 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients who have or are: 1. Orthopedics service patients having reverse shoulder replacement surgery 2. ASA class I, II, or III. 3. Patients at least 18 years old but less than 90 years old. 4. Patients giving informed consent. 5. Non-Emergency Surgery Exclusion Criteria: Patients who have or are: 1. An inability to cooperate during the block placement. 2. Patients who do not meet criteria for a regional block: such as those on anti-coagulation, 3. Significant pulmonary disease or allergy to medications used for peripheral nerve blocks (Exparel, Bupivacaine and Ropivacaine) 4. Neuropathy of the planned extremity to block 5. Documented Kidney Failure 6. Documented Liver Failure 7. A lack of or inability to give informed consent. 8. Currently incarcerated. 9. Pregnant 10. Unable to communicate in English 11. Chronic pre-operative opioid use (greater than 20 MME opioid used) 12. Fracture 13. Revision surgery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Iowa Hospital and Clinics
RECRUITINGIowa City, Iowa, 52242, United States
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Other studies related to the condition(s) this trial covers.
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- Two ways to numb the arm: which nerve block wins for hand surgery?
- Can a pre-surgery paracetamol and tramadol combo beat fentanyl for day-case pain?