Which nerve block wins the battle against Post-Surgery pain?
NCT ID NCT05179928
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers compare two ultrasound-guided nerve blocks, erector spinae plane block and rectus sheath block, to see which one controls pain better after supraumbilical surgery. Sixty adults having elective hernia repair under general anesthesia receive one of the two blocks after surgery. The trial measures how long until patients need rescue pain medicine and tracks their pain scores over 24 hours.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Erector spinae plane block and rectus sheath block, two ultrasound-guided nerve block procedures
- What this could lead to
- If one block proves better, it could become the preferred pain relief method after upper abdominal surgery, helping patients avoid opioid side effects like nausea and drowsiness.
- What could go wrong
- This small trial at one hospital may not show a clear winner, and results might not apply to other surgical centers or patient groups. Nerve blocks carry small risks of bleeding, infection, or nerve irritation.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status ≤ II * Age from 21 to 60 years * Body Mass Index (BMI) \< 35 kg/m² Exclusion Criteria: * American Society of Anesthesiologists (ASA) physical status \> II * Age \< 21 years or \> 60 years * Body Mass Index (BMI) ≥ 35 * Local infection at the puncture site * Altered mental status * Pregnant women * Allergy to study drugs * Chronic pain * Coagulation abnormalities or on anticoagulants * Severe hepatic or kidney disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Damanhour Teaching Hospital
RECRUITINGDamanhūr, El-Beheira, Egypt
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