Balloon coated with cancer drug could ease sinusitis
NCT ID NCT05883462
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a new approach for people with chronic sinusitis that keeps coming back. A balloon coated with the drug paclitaxel is inflated in the nasal passages to deliver medication directly to the tissue. The goal is to see if it is safe and can reduce symptoms and the need for repeat procedures. The trial involves 45 adults and is the first time this device is being tested in humans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
paclitaxel-coated nasal balloon
What this could lead to
If it works, this could offer a new, less invasive option to manage recurrent sinusitis and delay or avoid repeat sinus surgeries.
What could go wrong
This is a very early, first-in-human study with only 45 people. The drug coating may cause side effects, and the balloon procedure itself carries risks like bleeding or eye complications. Success is far from guaranteed.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sanatorio Americano Hospital
Asunción, Paraguay