Nasal spray ingredient may offer safer dental pulp treatment for kids

NCT ID NCT07675330

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether oxymetazoline, a common nasal decongestant, can replace sodium hypochlorite as a bleeding control agent during pulp treatment in children's baby teeth. About 50 Egyptian children aged 4-8 with decayed molars will receive either treatment. The goal is to see if oxymetazoline works as well or better, with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Oxymetazoline 0.05% nasal solution and Sodium Hypochlorite 5% solution
What this could lead to
If oxymetazoline works as well as sodium hypochlorite, it could offer a safer, less irritating option for stopping bleeding during dental pulp treatment in children.
What could go wrong
This is a small, early-stage trial with only 50 children, so results may not apply broadly. Oxymetazoline is not typically used for this purpose, and its effectiveness compared to the standard treatment is uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of dentistry, Cairo University.

    Cairo, Egypt

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Other studies related to the condition(s) this trial covers.