Eyedrop lifts droopy eyelids after facial paralysis?
NCT ID NCT05945615
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an FDA-approved eyedrop (oxymetazoline 0.1%) in 36 adults with eyelid droop caused by facial nerve miswiring after paralysis. The goal was to see if the drop could temporarily raise the eyelid, improve vision, and reduce abnormal muscle spasms. Researchers measured changes in eyelid position, facial function, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oxymetazoline 0.1% ophthalmic solution (Upneeq)
- What this could lead to
- If it works, this could offer a simple eyedrop treatment to temporarily lift the eyelid and improve vision and appearance in people with eyelid droop after facial paralysis.
- What could go wrong
- This is a small, completed trial with only 36 participants. The medication is already FDA-approved for other causes of eyelid droop, but its effect on droop due to nerve miswiring may be limited or not last long.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACQUIRED BLEPHAROPTOSIS DUE TO PERIOCULAR SYNKINESIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M.S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can targeted exercises and nerve stretching restore a symmetrical smile?
- Can a new turkish questionnaire capture the hidden impact of facial palsy?
- Skip the clinic: could a smartphone survey replace your post-surgery eye check?
- Eye drops could lift droopy eyelids without surgery
- New MRI method could help surgeons choose best treatment for facial paralysis
- Facial paralysis hope: new rehab techniques tested