Massive ATTR amyloidosis study aims to map disease journeys

NCT ID NCT06355934

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 12, 2026 · Updated 4 times

Summary

This observational study will analyze medical records from over 52,000 people with ATTR amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers want to learn about patients' symptoms, treatments, and outcomes in everyday medical practice. No new treatments are being tested; the goal is to gather information to improve understanding of the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand how ATTR amyloidosis progresses and how it is treated in real life, potentially improving future care.
What could go wrong: This is an observational study that does not test a new treatment, so it will not directly improve patient health. Results depend on the quality of existing medical records.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hereditary amyloidosis wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTR AMYLOIDOSIS

Contacts and locations

Locations

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COMPLETED

Eden Prairie, Minnesota, 55344, United States
Research Site
COMPLETED

Calgary, Alberta, T2P 4K7, Canada
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COMPLETED

Beijing, China
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COMPLETED

Changsha, China
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Chengdu, China
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Guangzhou, China
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Wuhan, China
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Horsens, Denmark
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COMPLETED

Berlin, Germany
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RECRUITING

Lecce, Italy
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RECRUITING

Messina, Italy
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RECRUITING

Milan, Italy
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COMPLETED

Tokyo, Japan
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RECRUITING

Lisbon, Portugal
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RECRUITING

Porto, Portugal
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COMPLETED

A Coruña, Spain
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Barcelona, Spain
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COMPLETED

Bilbao, Spain
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COMPLETED

El Palmar, Spain
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COMPLETED

Huelva, Spain
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COMPLETED

Las Palmas de Gran Canaria, Spain
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COMPLETED

Madrid, Spain
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COMPLETED

Majadahonda, Spain
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COMPLETED

Palma de Mallorca, Spain
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COMPLETED

Salamanca, Spain
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COMPLETED

Valencia, Spain
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COMPLETED

Södertälje, Sweden
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COMPLETED

Umeå, Sweden
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COMPLETED

London, United Kingdom

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