Pap test DNA may spot ovarian cancer years before symptoms
NCT ID NCT07556562
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether DNA from routine Pap smears can detect early signs of ovarian cancer in women with high-risk gene mutations. Researchers will compare genetic changes in Pap test samples with tissue removed during preventive surgery. If the method works, it could become a simple screening tool for early detection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple Pap-test-based screening to catch ovarian cancer early, potentially saving lives.
What could go wrong
This is an early validation study with only 260 participants. The test may not be accurate enough for widespread use, and results may not apply to all women.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario Agostino Gemelli, IRCCS
RECRUITINGRoma, Roma, 00186, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••