Could a simple pill replace daily IV drips for skin infections?
NCT ID NCT00323219
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether an oral antibiotic (moxifloxacin) works as well as a standard intravenous (IV) antibiotic (cefazolin) for treating moderate skin infections (cellulitis) in the emergency department. 390 patients with moderate cellulitis were treated either with daily IV antibiotics for 3-5 days or with oral moxifloxacin. The goal was to see if the oral option could be just as effective, potentially saving patients from daily hospital visits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
moxifloxacin (oral antibiotic) and cefazolin (intravenous antibiotic) with probenecid
What this could lead to
If oral moxifloxacin works as well as IV antibiotics, patients with moderate cellulitis could avoid daily hospital visits for IV treatment.
What could go wrong
This is a completed Phase 3 trial, so results are available. However, oral antibiotics may not be as effective for all types of infections, and some patients may still need IV therapy.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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St. Paul's Hospital, Providence Healthcare, Emergency Medicine
Vancouver, British Columbia, V1Y 1Z1, Canada