New biopsy method could sharpen prostate cancer detection

This study compares two biopsy methods in 572 men who have multiple suspicious spots on MRI but have never had a prostate biopsy. One method combines targeted biopsy with a wider sampling around each spot (perilesional biopsy), while the other combines targeted biopsy with standard systematic sampling. The goal is to see which approach more accurately finds aggressive prostate cancers and helps guide treatment decisions.