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New strategy aims to cut risks when emergency breathing tubes are needed

NCT ID NCT05539391

Recruiting now Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a combined approach for emergency breathing tube insertion in adults outside the hospital. The strategy includes a muscle relaxant (rocuronium), mask ventilation before intubation, and a special guide (gum elastic bougie). Researchers will compare complication rates in 1,500 patients to see if this method reduces severe events like cardiac arrest or low oxygen.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
rocuronium
What this could lead to
If successful, this could establish a safer standard method for emergency intubation, reducing life-threatening complications like cardiac arrest or low oxygen.
What could go wrong
This is a cluster trial with no blinding, so results may be influenced by how teams follow the protocol. The strategy may not work for all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Emergencies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EMERGENCIES OUT OF HOSPITAL SETTING TRACHEAL INTUBATION

Contacts and locations

Locations

  • AP-HP - Hôpital Avicenne

    RECRUITING

    Bobigny, 93000, France

  • AP-HP - Hôpital Henri Mondor

    RECRUITING

    Créteil, 94000, France

  • AP-HP - Hôpital Lariboisière

    RECRUITING

    Paris, 75013, France

  • AP-HP - Hôpital Necker

    RECRUITING

    Paris, 75730, France

  • AP-HP - Hôpital Pitié-Salpétrière

    RECRUITING

    Paris, 75013, France

  • AP-HP - Hôpital Raymond Poincaré

    RECRUITING

    Garches, 92380, France

  • CH Carnelle Portes de l'Oise

    RECRUITING

    Beaumont-sur-Oise, 95260, France

  • CH de Pontoise René Dubos

    RECRUITING

    Cergy-Pontoise, 95303, France

  • CH de Versailles - Site André Mignot

    NOT_YET_RECRUITING

    Le Chesnay, 78157, France

  • CHU Poitiers - Hôpital la Milétrie

    RECRUITING

    Poitiers, 86021, France

  • CHU Toulouse - Hôpital Purpan

    RECRUITING

    Toulouse, 31059, France

  • CHU d'Angers

    RECRUITING

    Angers, 49933, France

  • CHU de Bordeaux - Hôpital Pellegrin

    RECRUITING

    Bordeaux, 33000, France

  • CHU de Dijon

    NOT_YET_RECRUITING

    Dijon, 21000, France

  • CHU de Grenoble - Hôpital Nord La Tronche

    RECRUITING

    La Tronche, 38700, France

  • CHU de Montpellier Site Lapeyronie

    RECRUITING

    Montpellier, 34000, France

  • CHU de Nantes - Hôpital Hôtel Dieu

    RECRUITING

    Nantes, 44093, France

  • CHU de la Réunion - site Sud

    RECRUITING

    Saint-Pierre, 97448, France

  • GH Eaubonne Montmorency Hôpital Simone VEIL

    RECRUITING

    Eaubonne, 95600, France

  • GH Sud Ile de France

    RECRUITING

    Melun, 77000, France

  • GH Sélestat Obernai

    NOT_YET_RECRUITING

    Sélestat, 67 600, France

  • HCL - Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69003, France

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