Scientists test smarter settings for brain implants to stop epilepsy seizures

NCT ID NCT05493722

Recruiting now Symptom relief Sponsor: University of Minnesota Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adjusting the settings of an already-implanted deep brain stimulator can better control seizures in people with epilepsy that doesn't respond to medication. Researchers will try different combinations of stimulation strength, speed, and pulse width in 20 participants. The goal is to find the best settings for each person to reduce seizures and improve quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) parameter adjustments
What this could lead to: If successful, this could lead to a personalized way to adjust DBS settings that better controls seizures for each patient.
What could go wrong: This is a very early, small study (20 people) focused on measuring brain signals, not on proving seizure reduction. It may not lead to a widely usable treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEEP BRAIN STIMULATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Drug Resistant Epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP BRAIN STIMULATION REFRACTORY EPILEPSY

Contacts and locations

Locations

University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.