Could a simple amino acid boost seizure control in tough epilepsy?
NCT ID NCT06387186
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small study tested a leucine-enriched amino acid powder given alongside a classic ketogenic diet in 4 people with drug-resistant epilepsy. The main goal was to see if the powder is safe and tolerable. Researchers also checked if it helped with nutrition. Because it was a very early, single-arm trial with no placebo group, it can only hint at possible benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Leucine-enriched essential amino acid powder
What this could lead to
If it works, this could point toward a safe way to improve seizure control and nutrition for people with drug-resistant epilepsy who are already on a ketogenic diet.
What could go wrong
This is a very early, tiny study with only 4 participants and no comparison group. It only looks at safety, not whether seizures actually improve. Results may not apply to others.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States