Prostate cancer radiotherapy showdown: which technique wins?

NCT ID NCT03386045

Ongoing Disease control Sponsor: Royal North Shore Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares three different radiotherapy techniques for prostate cancer: standard treatment, a shorter course (SBRT), and a booster approach. Over 500 participants are being followed to see which method best controls cancer while minimizing side effects and preserving quality of life. The goal is to find the optimal balance of effectiveness and tolerability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiotherapy (SBRT, moderate hypofractionation, and standard radiotherapy plus SBRT booster)
What this could lead to: If successful, this study could identify which radiotherapy approach offers the best cancer control with fewer side effects, improving treatment decisions for prostate cancer patients.
What could go wrong: This is a phase-less comparative study, not a new drug trial. Results may show no clear winner, and individual outcomes vary. Side effects like urinary or bowel issues are possible with any radiotherapy.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Royal North Shore Hospital

St Leonards, New South Wales, 2065, Australia

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