Can tailored hepatitis c drugs cure infection in kidney patients?
NCT ID NCT07770984
First seen Aug 18, 2026 · Last updated Aug 18, 2026
Summary
This clinical trial aims to find the safest and most effective hepatitis C treatment for people with chronic kidney disease (CKD). Researchers will compare two drug combinations based on how well the kidneys are working: one for patients with moderate kidney function and another for those with severe impairment or on dialysis. The study will measure whether the virus is eliminated 12 weeks after treatment ends and will monitor liver and kidney health, along with quality of life, to ensure the therapy is both effective and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sofosbuvir and Daclatasvir, or Paritaprevir/Ombitasvir/Ritonavir with Ribavirin
- What this could lead to
- If successful, this could identify the best hepatitis C treatment for people with chronic kidney disease, potentially curing their infection and improving kidney and overall health.
- What could go wrong
- This is a mid-stage trial with a small number of participants, so results may not apply to everyone. The drugs may cause side effects or interact with kidney function, and the cure rate may be lower than hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tanta University, Internal Medicine Department, Nephrology and Dialysis Unite and Viral Committee
Tanta, Gharbia Governorate, 31719, Egypt
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