Genetic screening of 1,000+ endometrial cancer patients paves way for personalized care

NCT ID NCT03460483

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 31 times

Summary

This study screened over 1,000 women with endometrial cancer for specific DNA changes that can help doctors choose the most effective treatments. It also looked for inherited mutations linked to Lynch syndrome, which increases cancer risk in families. The goal was to improve personalized care and identify at-risk relatives who might benefit from early prevention.

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Contacts and locations

Locations

  • Aultman Health Foundation

    Canton, Ohio, 44710, United States

  • Mercy Health - St. Vincent Medical Center

    Toledo, Ohio, 43608, United States

  • MetroHealth Medical Center

    Cleveland, Ohio, 44109, United States

  • Ohio Health

    Columbus, Ohio, 43214, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Summa Akron City Hospital/Cooper Cancer Center

    Akron, Ohio, 44304, United States

  • TriHealth Cancer Institute-Westside

    Cincinnati, Ohio, 45245, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

Conditions

Explore the condition pages connected to this study.