Brain scans may predict opioid relapse risk
NCT ID NCT06800703
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This observational study at Yale University aims to understand how people with opioid use disorder (OUD) learn to avoid pain compared to healthy individuals. About 180 participants will perform a learning task inside an fMRI scanner to measure brain activity. Those with OUD will also be followed for a year to track their opioid use, helping researchers see if brain patterns can predict future use or relapse.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could reveal brain patterns that predict opioid relapse, pointing toward new behavioral or brain-based treatments.
What could go wrong
This is an early observational study, not a treatment trial. It may not lead to direct therapies, and results may not apply to all people with opioid use disorder.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Connecticut Mental Health Center, S105
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••